APTAMERES, MOLECULES D'ACIDE NUCLEIQUE, ANTICORPS SYNTHETIQUES ET COMPOSITIONS DESTINES A LA DETECTION DES MYCOPLASMA HYOPNEUMONIAE ET AU TRAITEMENT DE L'INFECTION AU MYCOPLASMA HYOPNEUMONIAE
MARCHAND, NORMAN J.,CALTAGIRONE, G. THOMAS,LIAO, ALBERT
申请号:
CA2940637
公开号:
CA2940637A1
申请日:
2016.08.30
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
In prior art there is a need for improved substances and methods for detectingMycoplasmaHyopneumoniae and preventing or treating infection of pulmonary epitheliumcells,particularly in swine. The present invention provides aptamers,polynucleotides, and nucleicacid molecules, which include a polynucleotide sequence capable ofspecifically bindingpolypeptides participating in M. Hyopneumoniae infection. Also provided aremethods ofusing nucleic acid molecules, polynucleotides and synthetic antibodiesdirected there againstfor detection, treating and neutralization of M. Hyopneumoniae infection.