The device for powdering a solid unit dosage form of medication and administering the powder form includes an applicator, a powdering tool and, in certain embodiments, a cap. The device is used to create a powder form from a solid unit dosage form, and then administer the powder form to a body cavity of a patient. The cap is provided with an integrated powdering tool, allowing an open end of an applicator barrel to be releasably covered thereby. Manipulation of the powdering tool creates the powder form through abrasion of a solid unit dosage form of the medication received within the barrel. The cap and powdering tool may then be removed, leaving the powder form of the solid unit dosage form to be administered to the body cavity, such as a patient's vagina or rectum.
