Luigi Marzilli;Malgorzata Lipowska;Andrew T. Taylor, Jr.
发明人:
Malgorzata Lipowska,Andrew T. Taylor, Jr.,Luigi Marzilli
申请号：
US12990144
公开号：
US09061077B2
申请日:
2009.05.05
申请国别(地区):
US
年份:
2015
代理人:
摘要：
This disclosure relates to the methods of imaging the kidneys and measuring renal function using the renal tracer 99mTc(CO)3(NTA) (technetium-99m tricarbonyl-nitrilotriacetic acid). The disclosure encompasses methods of imaging the kidneys and measuring effective renal plasma flow (ERPF) in an animal or human subject using renal scintigraphy, comprising administering to an animal or human subject an amount of a renal tracer, wherein the renal tracer comprises 99mTc-(CO)3(NTA). Another aspect of the disclosure are methods of measuring effective renal plasma flow in an animal or human subject, comprising administering to an animal or human subject an amount of a renal tracer, wherein the renal tracer comprises 99mTc-(CO)3(NTA), isolating a series of plasma samples from the animal or human subject after administering the renal tracer and quantitatively detecting the amount of the renal tracer in the biological samples.
