PCSK9 antibody, antigen-binding fragment thereof, and medicinal application thereof

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专利权人:

Jiangsu Hengrui Medicine Co.; Ltd.;Shanghai Hengrui Pharmaceutical Co., Ltd.;Jiangsu Hengrui Medicine Co., Ltd.

发明人:

Qu, Xiangdong,Ye, Xin,Xu, Shaoyu,Yuan, Bei,Cui, Dongbing,Hu, Qiyue,Zhang, Lei,Xu, Zhibin,Tao, Weikang,Zhang, Lianshan,Sun, Piaoyang

申请号：

AU2016382932

公开号：

AU2016382932A1

申请日:

2016.12.20

申请国别(地区):

AU

年份:

2018

代理人:

摘要：

The present invention provides a PCSK9 antibody, an antigen-binding fragment thereof, and a medicinal application thereof. Provided in the invention is a chimeric antibody and a humanized antibody, both comprising a CDR of the PCSK9 antibody, and a pharmaceutical composition comprising the PCSK9 antibody and an antigen-binding fragment thereof, and an application of the PCSK9 antibody as a lipid-lowering agent. The invention specifically relates to an application of a humanized PCSK9 antibody for preparing a pharmaceutical drug to treat a PCSK9-induced disease or symptom.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/