THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY;THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS
发明人:
Anton Wyss-Coray,John Vincent Pluvinage,Michael C. Bassik,Michael Haney,Benjamin Smith,Carolyn Bertozzi
申请号:
US16956339
公开号:
US20200317778A1
申请日:
2018.12.21
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Provided herein are compositions, methods, kits and systems for treating cells, tissues and subjects to alter age-related biology (e.g., to study or to treat age-related diseases and conditions). In particular, provided herein are compositions, methods, and uses for inhibition or modification of sialic acid or its cognate receptor to restore phagocytosis in aged cells.