A system is provided for fastening tissue. The system includes a fastening device designed to bias between an actuated state for delivering into tissue and a quiescent state for fastening the tissue. In an embodiment, the fastening device may include a plurality of coils between which tissue can be pinched or fastened. The system also includes a pathway along which the fastening device can be accommodated for subsequent delivery into the tissue, and an activation mechanism along the pathway to bias the fastening device into an activated state for delivery into the tissue. Fastening devices, and methods of fastening are also provided.