Mary M. Bendig,Olivier J. Leger,Jose Saldanha,Tarran S. Jones,Ted A. Yednock
申请号:
US12175116
公开号:
US08246958B2
申请日:
2008.07.17
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The invention provides methods of treatment using humanized immunoglobulins that specifically bind to alpha-4 integrin. The methods are useful for treatment of asthma, atherosclerosis, AIDS dementia, diabetes, inflammatory bowel disease, rheumatoid arthritis, transplant rejection, graft versus host disease, tumor metastasis, nephritis, atopic dermatitis, psoriasis, myocardial ischemia, and acute leukocyte mediated lung injury.