JASSEM MARCIN;GDANSKI UNIWERSYTET MEDYCZNY;SKRZYPSKI MARCIN
发明人:
SKRZYPSKI MARCIN,JASSEM JACEK
申请号:
PL38868109
公开号:
PL212748B1
申请日:
2009.07.30
申请国别(地区):
PL
年份:
2012
代理人:
摘要:
The invention relates to a method of determination of the risk of distant metastases in surgically treated patients with non-small cell lung cancer in stage I-IIIA wherein microRNA is extracted from a sample of primary tumor tissue, retrotranscribed into complementary DNA by reverse transcription, quantity of microRNA hsa-miR-660 is examined with the use of quantitative PCR method and the expression value of this microRNA is referred to the corresponding microRNA reference expression values in a disease recurrence prediction model in which low expression value of microRNA hsa-miR-660 is correlated to the high risk of distant metastases.