GODFRIN, YANN,BOURGEAUX, VANESSA,GAY, FABIEN,CORTESE, THOMAS
申请号:
SG11201606264S
公开号:
SG11201606264SA
申请日:
2015.02.12
申请国别(地区):
SG
年份:
2016
代理人:
摘要:
The invention relates to a pharmaceutical composition containing a PLP-dependent enzyme and optionally its cofactor, pyridoxal phosphate (PLP), and/or a phosphate or non-phosphate precursor of PLP, its use as a drug, its production method and a therapeutic treatment method related to it. The pharmaceutical composition comprises erythrocytes and a pharmaceutically acceptable vehicle, the erythrocytes encapsulating the PLP-dependent enzyme. The PLP-dependent enzyme may be methioninase, tyrosine phenol-lyase, tyrosine aminotransferase or cystathionine beta-synthase.