This invention relates to a device (10) for taking at least one sample of soft tissue from an organ, said device comprising a body (11) and a needle (12) formed by a . stylet and a cannula coaxial with said stylet. The device comprises a mechanism for arming the needle, designed for sequentially moving the cannula and then the stylet from a rest position wherein the stylet and the cannula are extended towards the outside of the body, to a shooting position wherein the stylet and the cannula are retracted towards the rear of the body, and a triggering mechanism designed to release the stylet then the cannula and to allow their displacement from the shooting position to the rest position. The cannula is coupled kinematically to a cannula slider (24) comprising at least one retaining element (26) for maintaining the cannula slider in a shooting position. The stylet is coupled kinematically to a stylet slider (30) comprising at least one retaining element (32) for maintaining the stylet slider in a shooting position and means for unlocking the cannula slider. This device is characterized in that the stylet (13) comprises a sampling tip (51) able to slide into the cannula (14) and a displacement rod (42) connecting said sampling tip with the stylet slider (30), the sampling tip (51) being separate from the displacement rod (42).La présente invention concerne un dispositif (10) pour prélever au moins un échantillon de tissu mou sur un organe, ledit dispositif comprenant un corps (11) et une aiguille (12) formée par un stylet et une canule coaxiale audit stylet. Le dispositif comprend un mécanisme pour armer l'aiguille, conçu pour déplacer séquentiellement le stylet, puis la canule d'une position de repos dans laquelle le stylet et la canule sont étendus vers l'extérieur du corps, à une position d'actionnement dans laquelle le stylet et la canule sont rétractés vers l'arrière du corps, et un mécanisme de déclenchement conçu pour libérer le stylet, puis la canule et permett
