PROBLEM TO BE SOLVED: To provide a new dihydroxyboryl group-containing, nitrogen-containing heterocyclic derivative, a medicine comprising the derivative as an active ingredient and a method for producing a dihydroxyboryl group-containing, nitrogen-containing heterocyclic derivative, which does not require many processes and has a slight environmental load.SOLUTION: The new dihydroxyboryl group-containing dihydroxypyrimidin-2-one (or thioketone) derivative, the dihydroxyboryl group-containing 1,4-dihydropyridine derivative and the dihydroxyboryl group-containing dihydropyrano[2,3-c]pyrazole compound are provided. The cancer therapeutic agent comprises the compound as an active ingredient. The one-pot synthesis method from a multicomponent raw material of the compound is provided.COPYRIGHT: (C)2012,JPO&INPIT【課題】新規なジヒドロキシボリル基含有含窒素複素環誘導体、及び該誘導体を有効成分とする医薬、及び、多工程を要せず環境への負荷が少ないジヒドロキシボリル基含有含窒素複素環誘導体の製造法の提供。【解決手段】新規なジヒドロキシボリル基含有ジヒドロキシピリミジン-2-オン(又は、チオケトン)誘導体、ジヒドロキシボリル基含有1,4-ジヒドロピリジン誘導体及びジヒドロキシボリル基含有ジヒドロピラノ[2,3-c]ピラゾール化合物、該化合物を有効成分とする癌治療薬、並びに、該化合物の多成分原料からのワンポット合成法。【選択図】なし
