The present invention provides a method for treating diabetes, a diabetes-associated condition or disorder, or symptoms thereof suffered by a subject such as a mammal (e.g. a human patient or a pet), comprising (1) placing multiple electrodes within at least one renal artery of the subject and against blood vessel wall of the at least one renal artery； (2) adhering a surface electrode on an external surface such as skin of the subject； and (3) releasing a therapeutically effective amount of radiofrequency energy through at least one of the multiple electrodes to nearby tissues, so as to increase the temperature of the nearby tissues and induce a thermal alteration of the nearby tissues.
