DERIVE DE PYRIDINE AMIDOPYRIMIDINE, SON PROCEDE DE PREPARATION ET UTILISATION

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专利权人:

INC.;SHANGHAI ALLIST PHARMACEUTICALS

发明人:

LUO, HUIBING,ZHOU, HUAYONG,WANG, SHUHUI,WU, YONG

申请号：

CA2956628

公开号：

CA2956628C

申请日:

2015.07.29

申请国别(地区):

CA

年份:

2018

代理人:

摘要：

The present invention relates to pyridinylaminopyrimidine derivativesrepresented by thefollowing formula (1), and pharmaceutically acceptable salts, preparationprocess and usethereof, wherein R1, R2, R3, R4, R5, m and A are defined as in thedescription.Pyridinylaminopyrimidine derivatives of the present invention can selectivelyinhibit theactivity of mutant-type epidermal growth factor receptor (EGFR), have a goodinhibition forthe cancer cell proliferation, and therefore can be used as a therapeuticagent for treatingtumors and relevant diseases.(see above formula)

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