Charles M. Cohen;Slobodan Vukicevic;Kuber T. Sampath
发明人:
Charles M. Cohen,Kuber T. Sampath,Slobodan Vukicevic
申请号:
US13079161
公开号:
US08748378B2
申请日:
2011.04.04
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention provides methods for the treatment, and pharmaceuticals for use in the treatment, of mammalian subjects in, or at risk of, acute renal failure, or subject to, or at risk of, inflammation, neutrophil-mediated cell damage, and apoptosis resulting from tissue damage or injury. The methods involve the administration of certain proteins of the osteogenic protein/bone morphogenetic protein (OP/BMP) family within the TGF-β superfamily of proteins.