The invention provides a signal synchronization device, which obtains electrocardiographic, heart sound signal calibration factors by performing time domain and frequency domain transformations for an electrocardiographic signal and a heart sound signal, and thereby perform calibration for the electrocardiographic signal and the heart sound signal to synchronize the electrocardiographic signal and the heart sound signal in time domain, such that a diagnosis rate for cardiovascular disease is increased. Moreover, the invention further provides a stethoscope with signal synchronization processing, an auscultation information output system and a symptom diagnosis system capable of signal synchronization.本發明提供一種訊號同步處理裝置，通過針對心電訊號與心音訊號執行時域與頻域的轉換處理，以得到心電、心音訊號調校因子，並據以分別針對心電訊號與心音訊號進行調校處理，而使心電訊號與心音訊號在時域上同步，藉以提高針對心血管疾病的診斷率。此外，本發明復提供具有訊號同步處理功能的聽診器、聽診資訊輸出系統與病徵診斷系統。
