Eli M. Wallace;Joseph P. Lyssikatos;Allison L. Marlow;T. Brian Hurley
发明人:
Eli M. Wallace,Joseph P. Lyssikatos,Allison L. Marlow,T. Brian Hurley
申请号：
US12824559
公开号：
US08178693B2
申请日:
2010.06.28
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Disclosed are compounds of the Formulaand pharmaceutically acceptable salts and prodrugs thereof, wherein A, R1, R2, R7, R8, and R9 are as defined in the specification. Such compounds are MEK inhibitors and useful in the treatment of hyperproliferative diseases, such as cancer and inflammation, in mammals. Also disclosed is a method of using such compounds in the treatment of hyperproliferative diseases in mammals, and pharmaceutical compositions containing such compounds.
