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Compound having somatostatin receptor agonistic activity and pharmaceutical use thereof
专利权人:
ONO PHARMACEUTICAL CO.; LTD.
发明人:
Akiharu Ishida,Takeshi Matsushita,Tetsuya Sekiguchi,Yasuyuki Okabe,Tatsuya Komagata,Takuya Nishio
申请号:
US15025739
公开号:
US09643951B2
申请日:
2014.09.29
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention provides a somatostatin receptor subtype 2 agonist. A disclosed compound represented by the general formula (I):wherein all symbols have the same definitions as described in the specification;a salt thereof, an N-oxide thereof or a solvate thereof, or a prodrug of the foregoing is a low-molecular compound having strong somatostatin receptor subtype 2 agonistic activity, and thus can be administered in a simple manner, has high stability and has low toxicity. Therefore, the present compound is useful for prophylaxis and/or therapy of somatostatin-related diseases such as acromegaly and gastrointestinal obstruction.
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