您的位置: 首页 > 农业专利 > 详情页

NOVEL DIHYDROPYRIDOISOQUINOLINONES AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF INFLAMMATORY DISORDERS
专利权人:
GALAPAGOS NV
发明人:
MENET, Christel, Jeanne, Marie,DOYON, Julien, Georges, Pierre-Olivier,CLAES, Pieter, Isabelle, Roger,ALLART, Brigitte,DE WACHTER, Maxim, Maria, Paul,TRICARICO, Giovanni, Alessandro
申请号:
PH12017501911
公开号:
PH12017501911A1
申请日:
2017.10.19
申请国别(地区):
PH
年份:
2018
代理人:
摘要:
A compound according to Formula (I): wherein R1, LA, CyA, RA, R2, R3, and R4 are as described herein. The present invention relates to novel compounds according to Formula I that antagonize GPR84, a G-protein-coupled receptor that is involved in inflammatory conditions, and methods for the production of these novel compounds, pharmaceutical compositions comprising these compounds, and methods for the prevention and/or treatment of inflammatory conditions, pain, neuroinflammatory conditions, neurodegenerative conditions, infectious diseases, autoimmune diseases, endocrine and/or metabolic diseases, cardiovascular diseases, leukemia, and/or diseases involving impairment of immune cell functions by administering a compound of the invention.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充