Optical objective dimensioned to operate as part of intravascular endoscope probe and including first and second groups of lens elements. The first group of lens elements includes a first meniscus lens with a negative dioptric power and a first optical doublet. The second group of lens elements include a sequence of second, third, and fourth optical doublets and a second meniscus lens with a positive dioptric power. At least one of the first and second groups of lens elements includes an aspheric refractive surface, thereby reducing distortion down to under 1% for field angles up to at least 40 degrees. Methods for using same, including embodiments with such multiple optical objectives used for acquisition of images of targets with fixed FOV and image fusion, providing enhanced imaging data for target analysis.
