Conjugates comprising hydroxyalkyl starch and a cytotoxic agent and process for their preparation

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专利权人:

Sandeep Grewal;Fresenius Kabi Deutschland GmbH;Nitin Gupta;Sandeep Kaur;Hemant Singh;Lahiri Saswata;Sunil Sanghani;Azim Abul

发明人:

Knoller, Helmut,Heckmann, Dominik,Hacket, Frank,Zander, Norbert,Nocken, Frank,Saswata, Lahiri,Gupta, Nitin,Sanghani, Sunil,Abul, Azim,Singh, Hemant Kumar,Grewal, Sandeep,Kaur, Sandeep

申请号：

AU2011276120

公开号：

AU2011276120B2

申请日:

2011.07.11

申请国别(地区):

AU

年份:

2013

代理人:

摘要：

The present invention relates to a hydroxyalkyl starch conjugate and a method for preparing the same, said hydroxyalkyl starch conjugate comprising a hydroxyalkyl starch derivative and a cytotoxic agent, the cytotoxic agent comprising at least one secondary hydroxyl group, wherein the hydroxyalkyl starch is linked via said secondary hydroxyl group to the cytotoxic agent. The conjugate according to the present invention has a structure according to the following formula HAS'(-L-M)

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/