TU, BENJAMIN PANG HSIEN,杜邦宪,杜邦憲,CHEN, RITA PY,陈佩烨,陳佩燁,HUANG, JOSEPH JEN TSE,黄人则,黃人則,CHERN, YIJUANG,陈仪庄,陳儀莊,JANG, YU SONG,郑育淞,鄭育淞,LAI, XIANG ME,赖享玫,賴享玫
申请号:
TW104124329
公开号:
TW201617089A
申请日:
2015.07.27
申请国别(地区):
TW
年份:
2016
代理人:
摘要:
Bipartite molecules comprising a peptide affinity moiety and at least one charged moiety and uses thereof in reducing formation of abnormal protein aggregate and treating diseases associated with such abnormal protein aggregate, including neurodegenerative disease characterized by formation of protein aggregates.本發明係關於包括胜肽親和性部分及至少一個帶電部分之雙鏈(Bipartite)分子,及其於減少異常蛋白聚集體之形成及治療與此異常蛋白聚集體相關之疾病(包含特徵在於蛋白聚集體形成之神經退化性疾病)之用途。