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High-concentration antibody and protein formulations
专利权人:
GENENTECH, INC.; INC.;NOVARTIS AG;GENENTECH
发明人:
LIU, JUN,SHIRE, STEVEN
申请号:
DK04759018
公开号:
DK1610820T4
申请日:
2004.03.29
申请国别(地区):
DK
年份:
2013
代理人:
摘要:
The present application relates to highly concentrated antibody and protein formulations with reduced viscosity that are stable, relatively isotonic and are of low turbidity. The formulations are particularly suitable for subcutaneous administration. The application further describes articles of manufacture containing such formulations and methods for using them to treat disorders treatable by the formulated antibody or protein. The formulations comprise arginine-HCl, histidine and polysorbate.
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