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Fused pyrrolidino-cyclopropane derivatives as selective 11-beta-hydroxysteroid dehydrogenase type 1 inhibitors
专利权人:
Serge Christmann-Franck;Franck Lepifre;Didier Roche;Denis Carniato;Eric Valeur;Fabien Schmidlin
发明人:
Eric Valeur,Franck Lepifre,Didier Roche,Denis Carniato,Serge Christmann-Franck,Fabien Schmidlin
申请号:
US13061238
公开号:
US08486964B2
申请日:
2009.08.05
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention relates to fused pyrrolidino-cyclopropane derivatives according to formulae (I) to (IV) as selective inhibitors of the enzyme 11-beta-hydroxysteroid dehydrogenase type 1 (11-β-HSD-1) and the use of such compounds for the treatment and/or prevention of metabolic syndrome, diabetes, insulin resistance, obesity, lipid disorders, glaucoma, osteoporosis, cognitive disorders, anxiety, depression, immune disorders, hypertension and other diseases and conditions.
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中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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