Savory, Edward,Pritchard, Martyn,Higginbottom, Michael,ONeil, William John
申请号：
AU2014372326
公开号：
AU2014372326A1
申请日:
2014.12.22
申请国别(地区):
AU
年份:
2016
代理人:
摘要：
The invention relates to pharmaceutically active compounds having improved pharmacokinetic properties and being useful for the treatment or prevention of a range of conditions including migraine, epilepsy, non-epileptic seizures, brain injury (including stroke, intracranial haemorrhage and trauma induced) or cardiovascular diseases including myocardial infarction, coronary revascularization or angina. The compounds of the invention form a novel group of related prodrugs of formula (II), where Ar is a 3-chloro-4-fluorophenyl ring, a 3-chlorophenyl ring or a 4-fluorophenyl ring and R is a hydrolysable group comprising an amino group or an acidic group.
