Provided herein are devices comprising a stent and a coating on said stent comprising a polymer and an active agent, wherein the active agent comprises at least one of: extracellular matrix and an extracellular matrix component. Provided herein are methods of preparing a device comprising a stent and a coating on said stent said method comprising: providing a stent and forming a plurality of layers on said stent wherein the coating comprises a polymer and at least one of said layers comprises one or more active agents wherein at least a portion of the active agent comprises at least one of extracellular matrix and an extracellular matrix component.
