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Method for production of directly compressible ibuprofen formulations
专利权人:
Anisul Quadir;Kathrin Meyer-Boehm;Karl Kolter
发明人:
Kathrin Meyer-Boehm,Karl Kolter,Anisul Quadir
申请号:
US12089416
公开号:
US08846085B2
申请日:
2006.10.05
申请国别(地区):
US
年份:
2014
代理人:
摘要:
A directly tabletable ibuprofen formulation comprising a) 50-99% by weight of crystalline ibuprofen, b) 1-15% by weight of a finely divided excipient with a surface area of at least 100 m2/g, and c) 0-40% by weight of further excipients, with the proviso that the total amount of components a) to c) corresponds to 100% by weight, where at least 50% of the surface of the ibuprofen crystals are covered with the finely divided excipient.
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