Brid Devlin,Jonathon Daryll Holt,Andrew Nathan Brimer,Jeremy Peter Nuttall,Karl Malcolm,Susan Margaret Fetherston,Peter John James Boyd
申请号:
US14540530
公开号:
US20150136143A1
申请日:
2014.11.13
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention provides improved intravaginal drug delivery devices, i.e., intravaginal rings, useful for the prophylactic administration of dapivirine in combination with either an antimicrobial compound or a contraceptive to a human. The present invention also provides methods of blocking DNA polymerization by an HIV reverse transcriptase enzyme, methods of preventing HIV infection in a female human, methods of treating HIV infection in a female human, methods of preventing unintended pregnancy in a female human, and methods of preparing intravaginal rings.