The invention relates to a composition which induces, in a host, a cytotoxic cellresponse directed against cells expressing an antigen, in particular tumourcells, and which comprises red blood cells containing said antigen. These redblood cells may be in the form of an immune complex with an immunoglobulin, in particularIgG, which recognizes an epitope at the surface of the red blood cells, and/orbe heat-treated or chemically treated so as to promote phagocytosis of said redblood cells by dendritic cells. As a variant, the red blood cells may be xenogenicred blood cells. The invention also relates to a therapeutic especially anti-tumourvaccine containing such a composition.
