The present invention discloses an ovine enoxaparin sodium, a preparation method therefor, and an application thereof. The ovine enoxaparin sodium is prepared from ovine heparin. Compared with enoxaparin sodium derived from porcine intestinal mucosa heparin, both the chemical structures (disaccharide compositions) and the physiochemical properties are different. Through process of optimization and precipitation, the ovine enoxaparin sodium prepared meets the enoxaparin sodium specifications in the USP 37 and the EP 8.0 as well as specifications in current editions of the USP 39 and the EP 8.6. Also provided are two types of ovine enoxaparin sodium injections, preparation methods therefor, and anticoagulation properties in animal model. The raw material used in the preparation is ovine, which is a Halal material compared to porcine enoxaparin sodium. Therefore, the ovine enoxaparin sodium and the injections thereof are an Halal anticoagulant medicine.
