Disclosed herein are compounds, pharmaceutical compositions, and related methods for the treatment of viral infection, including RNA viral infection in subjects. The compounds, pharmaceutical compositions, and methods can modulate the innate immune antiviral response in vertebrate cells, including activating the RIG-I pathway.本文揭示用於治療個體病毒感染(包括RNA病毒感染)之化合物、醫藥組合物及相關方法。該等化合物、醫藥組合物及方法可調節脊椎動物細胞中之先天性免疫抗病毒反應,包括活化RIG-I路徑。