Administration of lorcaserin to individuals with renal impairment

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专利权人:

ARENA PHARMACEUTICALS INC.

发明人:

ANDERSON CHRISTEN M.,SHANAHAN WILLIAM R.

申请号：

NZ60826611

公开号：

NZ608266A

申请日:

2011.08.31

申请国别(地区):

NZ

年份:

2015

代理人:

摘要：

Provided is the treatment of obesity and related conditions using (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine (lorcaserin), with consideration of a patient&rsquos renal function. It appears that patients with severe renal impairment or end stage renal disease (ESRD) are exposed to greater metabolite levels when they are administered lorcaserin so the use of lorcaserin is contraindicated in these patients.

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中国工程科技知识中心

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http://www.ckcest.cn/home/