Provided herein are Aminopurine compounds of Formula I:(I) or pharmaceutically acceptable salts, tautomers, isotopologues, or stereoisomers thereof, wherein R1, R2, and R3are as defined herein, compositions comprising an effective amount of an Aminopurine Compound, and methods for treating or preventing animal and human protozoal infections.本發明提供式I胺基嘌呤化合物:(I) 或其醫藥上可接受之鹽、互變異構體、同位素體或立體異構體,其中R1、R2及R3係如本文所定義,包含有效量之該胺基嘌呤化合物的組合物,及治療或預防動物及人類之原蟲感染的方法。無