Andreas Schall,Jürgen Klar,Mario Lobell,Hartmut Schirok,Joachim Telser,Steffen Müller,Dirk Brohm,Hans Briem,Hannah Jörißen,Joerg Keldenich,Michael Böttger,Georges Von Degenfeld,Thomas Schlange,Ulf Böm
申请号:
US15529043
公开号:
US10047096B2
申请日:
2015.11.23
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present application relates to novel (3-hydroxyphenyl)amino-substituted pyrido[2,3-b][1,5]benzodiazepin-5-one derivatives, to processes for preparation thereof, to the use thereof alone or in combination for treatment and/or prevention of diseases and to the use thereof for production of medicaments for treatment and/or prevention of diseases, especially of angiogenic disorders and hyperproliferative disorders in which neovascularization plays a role, for example ophthalmological disorders and cancers and tumours. Such treatments can be effected as monotherapy or else in combination with other medicaments or further therapeutic measures.