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Nanoparticle composition and methods to make and use the same
专利权人:
Monica Jablonski
发明人:
Monica Jablonski,Mallika Palamoor
申请号:
US13767734
公开号:
US09149426B2
申请日:
2013.02.14
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention provides a novel nanoparticle drug delivery system generated from poly(ortho ester) polymers with sustained drug release capability and can be functionalized to allow for systemic delivery to various organ systems throughout the body. One important aspect of this invention is that the nanoparticle drug delivery system generated from poly(ortho ester) polymers encapsulate several types of drugs in poly(ortho ester) nanoparticles, including but not limited to lipophilic, hydrophilic small and large molecules and also hydrophilic and lipophilic dyes by adopting appropriate emulsion techniques. These poly(ortho ester) nanoparticles are biodegradable, biocompatible and controlled release drug delivery system with zero order kinetics, which can be used in various biomedical applications such as eye-related diseases, cancer, arthritis, etc.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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