DERIVES DE 4-(ANILINO SUBSTITUE)QUINAZOLINE A TITRE D'INHIBITEURS DE TYROSINE KINASE

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专利权人:

QILU PHARMACEUTICAL CO.; LTD

发明人:

WANG, JINGYI,FAN, CHUANWEN,ZHANG, LONG,GUO, ZONGRU,LI, YING,YANG, SHAOBO,YAN, SHOUSHENG,ZHU, JIANRONG,YANG, QINGMIN,ZHANG, MINGHUI

申请号：

CA2775601

公开号：

CA2775601C

申请日:

2010.09.20

申请国别(地区):

CA

年份:

2017

代理人:

摘要：

The present invention relates to 4-(substituted anilino)-quinazolinederivativesas tyrosine kinase inhibitors. Specifically, compounds of formula I, orpharmaceutically acceptable salts or solvates thereof are disclosed, in whicheachsubstitutent in formula I is defined in the description. Preparation method ofthecompounds of formula I, pharmaceutical compositons and pharmaceutical usesthereof are also disclosed. The compounds of formula I are effective tyrosinekinaseinhibitors.(see formula I)

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