Olivier Alexis Georges QUEROLLE,Vineet PANDE,Barbara HERKERT,Daniel Jason KROSKY,Aaron Nathaniel PATRICK,Patric René ANGIBAUD
申请号:
MX2019002959
公开号:
MX2019002959A
申请日:
2017.09.13
申请国别(地区):
MX
年份:
2019
代理人:
摘要:
The present invention relates to pharmaceutical agents useful for therapy and/or prophylaxis in a mammal, and in particular to fused bicyclic compounds, pharmaceutical composition comprising such compounds, and their use as menin/MLL protein/protein interaction inhibitors, useful for treating diseases such as cancer, myelodysplastic syndrome (MDS) and diabetes.La presente invencion se refiere a agentes farmaceuticos utiles para tratamiento y/o profilaxis en un mamifero, y en particular a compuestos biciclicos condensados, composición farmaceutica que comprende dichos compuestos, y su uso como inhibidores de la interaccion de proteina/proteina menina/MLL, utiles para tratar enfermedades tales como cancer, síndrome mielodisplasico (MDS) y diabetes.