#$%^&*AU2011203234B220130110.pdf#####ABSTRACT OF THE DISCLOSURE An air delivery system includes a controllable flow generator operable to generate a supply of pressurized breathable gas to be provided to a patient for treatment and a pulse oximeter configured to determine a measure of patient effort during a treatment period and provide a patient effort signal for input to control operation of the flow generator. See Figure 2 252110 Sensor Analysis Target Action Parameter * Amplitude processing - 1 Respiratory High pass filter rate & effort Synchrony (<;10 sec time ntrols (rate, constant) Pressure Amplitude I support titration processing Low pass filter (>;20+ sec lime EEIP/CPAF constant) titration Vascular compliance / Morphological SNS activity processing -SDB3 screening ximater Oicrotic notch diagnosis plethysmogram analysis Saturation EEP/CPAP reduction if venos pulsation increasesreutn Morphological fotowiip increase in CPAPEEP processing ven~ous Impeded pulsation venous return Reporting i analysis CHF status Clinical management.' Morphological/ Long term decevte in venus rhythm pulisaion uoled - improved CV si=3CS Comorbidities bily Cardiac tIming irregularities/ Warhythmla A~letCoECG (i' avaable - '--~'-ac-ti Pulse transit morbidity time FIG. 2