Katharina Nora Steinitz,Paula Maria Wilhelmina van Helden,Birgit Maria Reipert,Hans-Peter Schwarz,Hartmut Ehrlich
申请号:
US15341936
公开号:
US20170267743A1
申请日:
2016.11.02
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention is related to peptides that can be used to reduce the immune response against FVIII or to induce tolerance to human FVIII in patients with, e.g., hemophilia A. Furthermore, the peptides can be used for immunodiagnostic purposes to detect FVIII-specific CD4+ T cells to monitor patients with hemophilia A during replacement therapy and during immune tolerance induction therapy.