BEARSS, DAVID J.,LIU, XIAO-HUI,VANKAYALAPATI, HARIPRASAD,XU, YONG
申请号:
CA2667487
公开号:
CA2667487C
申请日:
2007.11.06
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
The present invention provides protein kinase inhibitors comprising imidazo[1,2-b]pyridazine and pyrazolo[1,5-a]pyrimidine compounds of the following structure (I) and (II), or a stereoisomer, prodrug or pharmaceutically acceptable salt thereof, wherein R, R1, R2 and X are as defined herein. Compositions and methods for using the same in the treatment of cancer and other Pim kinase-associated conditions are also disclosed.