CLOYD, James,BIRNBAUM, Angela,LEPPIK, Ilo,COLLINS, Stephen
申请号:
AU2013200204
公开号:
AU2013200204B2
申请日:
2013.01.15
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
#$%^&*AU2013200204B220140731.pdf#####ABSTRACT The present invention is directed to a carbamazepine-cyclodextrin inclusion complex useful for the parenteral administration of carbamazepine. The carbamazepine-cyclodextrin inclusion complex is prepared by the admixture of a modified cyclodextrin and carbamazepine in a physiologically acceptable fluid. Modified cyclodextrins include 2hydroxypropyl-beta-cyclodextrin and sulfoalkyl cyclodextrins. More particularly, the sulfoalkyl cyclodextrins are those described and disclosed in U.S. Patent Nos. 5,134,127 and 5,376,645. A physiologically acceptable fluid includes sterile isotonic water, Ringer's lactate, D5W (5 % dextrose in water), physiological saline, and similar fluids suitable for parenteral administration. 39882201 (GHMatters) P77458AU.1 10/01/13