TRAITEMENTS D'ASSOCIATION POUR LE TRAITEMENT DE CANCERS ASSOCIES A BCMA ET DE TROUBLES AUTO-IMMUNS

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专利权人:

FRED HUTCHINSON CANCER RESEARCH CENTER

发明人:

RIDDELL, STANLEY R.,GREEN, DAMIAN,HILL, TYLER

申请号：

CA3052779

公开号：

CA3052779A1

申请日:

2018.02.16

申请国别(地区):

CA

年份:

2018

代理人:

摘要：

The present disclosure relates to methods for using BCMA-specific binding molecules (such as a BCMA-specific chimeric antigen receptor or antibody) in combination with ?-secretase inhibitors, which can be done concurrently or sequentially, to treat or prevent a B-cell related proliferative disease, such as a cancer or autoimmune disease, or the like. A BCMA-specific binding molecule in combination with ?-secretase inhibitor can be used in, for example, adoptive immunotherapy.

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