This invention designates the multilayer structure for the buccal cavity which includes the bioactive substance which is suited for the dosage inside the buccal cavity which supports in the sugar and that the production method is offered as topic, the transparency or the translucency which designates the sugar composition as subject is laminated on more, more, furthermore, sugar constitution differs from the aforementioned more sugar composition the multilayer structure for the buccal cavity which consists of with the opaque second layer which includes the bioactive substance which is suited for the dosage inside the buccal cavity which supports in the crystal sugar, or, the description above more and in addition to the aforementioned second layer, it was laminated on the aforementioned second layerThe aforementioned topic is solved with the multilayer structure for the buccal cavity which consists of the opaque third layer which designates the sugar composition as subject and offering the production method.本発明は、糖質に担持された口腔内投与に適した生理活性物質を含む口腔用多層構造物とその製造方法を提供することを課題とし、糖質組成物を主体とする透明乃至半透明な第一層と、第一層上に積層され、結晶糖質に担持された口腔内投与に適した生理活性物質を含む不透明な第二層とからなる口腔用多層構造物、または、前記第一層及び前記第二層に加え、更に、前記第一層の糖質組成物とは糖組成が異なる、前記第二層上に積層された糖質組成物を主体とする不透明な第三層とからなる口腔用多層構造物とその製造方法を提供することにより前記課題を解決する。
