method of obtaining \u043d\u0430\u0442\u0438\u0432\u043d\u043e\u0433\u043e protein \u043f\u0440\u043e\u043b\u043e\u043d\u0433\u0438\u0440\u0443\u044e\u0449\u0435\u0433\u043e actions of polymer \u043d\u0430\u043d\u043e\u0441\u0444\u0435\u0440 and \u0440\u0435\u0437\u043e\u0440\u0431\u0438\u0440\u0443\u0435\u043c\u044b\u0445 \u043c\u0438\u043a\u0440\u043e\u0441\u0444\u0435\u0440 for delivery
Александр Данилович,Ольга Александровна,Сергей Васильевич,Илья Владимирович
申请号:
EA201700521
公开号:
EA201700521A2
申请日:
2017.11.23
申请国别(地区):
EA
年份:
2018
代理人:
摘要:
the invention belongs to the field of medicine, in particular to \u043d\u0430\u043d\u043e\u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0435,which uses \u0431\u0438\u043e\u0434\u0435\u0433\u0440\u0430\u0434\u0438\u0440\u0443\u0435\u043c\u044b\u0435 \u043d\u0430\u043d\u043e\u0441\u0444\u0435\u0440\u044b and \u043c\u0438\u043a\u0440\u043e\u0441\u0444\u0435\u0440\u044b for inclusion in their composition of biologically active proteins to stabilize their structure.this method provides for the inclusion of \u0433\u0438\u0441\u0442\u043e\u043d\u0430 of animal origin in the \u043c\u0430\u0442\u0440\u0438\u043a\u0441\u0430 \u043d\u0430\u043d\u043e\u0441\u0444\u0435\u0440 diameter of not more than 1000 nm, which receive n and the basis of \u0434\u0435\u043a\u0441\u0442\u0440\u0430\u043d\u0430,and the subsequent incorporation \u043d\u0430\u043d\u043e\u0441\u0444\u0435\u0440 with \u0433\u0438\u0441\u0442\u043e\u043d\u043e\u043c in \u0440\u0435\u0437\u043e\u0440\u0431\u0438\u0440\u0443\u0435\u043c\u044b\u0435 \u043c\u0438\u043a\u0440\u043e\u0441\u0444\u0435\u0440\u044b, which are based on the copolymer polylactic acid - \u0433\u043b\u0438\u043a\u043e\u043b\u0438\u0434\u0430.the release of \u0440\u0435\u0437\u043e\u0440\u0431\u0438\u0440\u0443\u0435\u043c\u044b\u0445 \u0433\u0438\u0441\u0442\u043e\u043d\u0430 \u043c\u0438\u043a\u0440\u043e\u0441\u0444\u0435\u0440 occurs during a period of not less than 50 days.provided by the invention ensures that the \u043d\u0430\u0442\u0438\u0432\u043d\u043e\u0439 protein structure through its inclusion in the polymer \u043d\u0430\u043d\u043e\u0441\u0444\u0435\u0440 and enhances the reliability and simplifies the method of obtaining protein \u043d\u0430\u0442\u0438\u0432\u043d\u043e\u0433\u043e stahail of \u043d\u0430\u043d\u043e\u0441\u0444\u0435\u0440 and \u0440\u0435\u0437\u043e\u0440\u0431\u0438\u0440\u0443\u0435\u043c\u044b\u0445 \u043c\u0438\u043a\u0440\u043e\u0441\u0444\u0435\u0440 intended for extension of physiological actions \u043d\u0