Thong-Gyu Jin,Yo Kyung Chung,Sang Hoon Paik,Yoo Chang Park,Jinwook Seo,Yong Woon Choi,Jong Mun Son,Yong-Chul Kim
申请号:
US15184406
公开号:
US09896672B2
申请日:
2016.06.16
申请国别(地区):
US
年份:
2018
代理人:
摘要:
A composition comprising recombinant iduronate-2-sulfatase (IDS) and a method for producing a purified recombinant IDS are provided. The glycosylation pattern and formylglycine content of the IDS composition are different from those of ELAPRASE® and have superior pharmaceutical efficacy and are safer than the conventional agent and thus can be effectively used for the therapy of Hunter syndrome.