METHODS OF USING (+)-1,4-DIHYDRO-7-[(3S,4S)-3-METHOXY-4-(METHYLAMINO)-1-PYRROLIDINYL]-4-OXO-1-(2-THIAZOLYL)-1,8-NAPHTHYRIDINE-3-CARBOXYLIC ACID FOR TREATMENT OF ANTECEDENT HEMATOLOGIC DISORDERS

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专利权人:

Inc.;Sunesis Pharmaceuticals

发明人:

Michelson, Glenn

申请号：

AU2017201156

公开号：

AU2017201156A1

申请日:

2017.02.21

申请国别(地区):

AU

年份:

2017

代理人:

摘要：

#$%^&*AU2017201156A120170316.pdf#####ABSTRACT Methods of treating, preventing or managing antecedent fematologic disorders, such as myelodysplastic syndrome, including chronic myelomonocytic leukemia are disclosed. The methods encompass the administration of SNS-595. Also provided are methods of treatment 5 using this compound with chemotherapy, radiation therapy, hormonal therapy, biological therapy or immunotherapy. In certain embodiments, the method of treatment comprise administering SNS-595 in combination with cytarabine. Pharmaceutical compositions and single unit dosage forms suitable for use in the methods are also disclosed.

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