A pharmaceutical composition for inhibiting angiogenesis and the application thereof are disclosed. It comprises an ingredient of 2-methoxy-6-methyl-p-benzoquinone or 2,3-dimethoxy-5-methyl-p-benzoquinone or 2-hydroxy-5-methoxy-3-methyl-p-benzoquinone, and appropriate medical acceptability excipient or carrier. The pharmaceutical composition is used for inhibiting angiogenesis so as to treat or prevent related diseases of angiogenesis.一種抑制血管新生之醫藥組合物及其應用，包括2-甲氧基-6-甲基-p-苯醌(2-methoxy-6-methyl-p-benzoquinone)或2,3-二甲氧基-5-甲基-p-苯醌(2,3-dimethoxy-5-methyl-p-benzoquinone)或2-羥基-5-甲氧基-3-甲基-p-苯醌(2-hydroxy-5-methoxy-3-methyl-p-benzoquinone)之一成分，以及適當之醫藥可接受性賦形劑或載劑，該醫藥組合物係用以抑制血管新生，進而治療或預防血管新生相關疾病。
