Ytzhack Marmary;Jonathan H. Axelrod;Eithan Galun;Stefan Rose-John
发明人:
Jonathan H. Axelrod,Eithan Galun,Stefan Rose-John,Ytzhack Marmary
申请号:
US12745049
公开号:
US08372389B2
申请日:
2008.11.27
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention relates to methods for preventing or treating toxicities associated with exposure to ionizing radiation or to chemotherapy. Particularly, the present invention relates to methods for preventing or treating toxicities associated with radiation or chemotherapy comprising administering to a subject in need of such treatment polypeptide complexes comprising an IL-6 linked to a soluble IL-6 receptor, the polypeptide complexes capable of preventing or treating toxicities, particularly xerostomia.