The invention provides compounds of Formula (I) and pharmaceutically acceptable salts thereof. The Formula (I) imidazotriazines inhibit protein kinase activity thereby making them useful as anticancer agents.本發明提供式(I)化合物及其醫藥學上可接受之鹽。該等式(I)之咪唑并三可抑制蛋白質激酶活性,由此適用為抗癌劑。