Maria Gonzalez Ferreiro,Lutz Kröhne,Achim Müller,Katharina Schmid,Andreas Voigt
申请号：
US12012870
公开号：
US08147897B2
申请日:
2008.02.06
申请国别(地区):
US
年份:
2012
代理人:
摘要：
A method for making an article comprising a core material and a coating thereon, the method comprising the steps of:(a) providing the core material(b) applying one or more layers of a crosslinkable polycationic material, wherein the polycationic material is a reaction product of:(i) an epoxide of formula (I)wherein X equals bromo, chloro, iodo, or cyano, and R1, R2, R3, R4, independently of one another, are selected from the group consisting of hydrogen, linear or branched C1-C6-alkyl, and linear or branched C1-C6-alkyl which is substituted with halogen, and(ii) a polymer having repeating units comprising one or more secondary or tertiary amine group(s)(c) applying one or more layers of a polyanionic material and(d) cross-linking the layers of polyelectrolytes formed by steps (b) and (c).The articles obtainable by the method of the invention have desirable characteristics regarding adherence to the core material, durability, hydrophilicity, and wettability and are thus useful for the manufacture of medical articles such as ophthalmic devices.
