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Paliperidone implant formulation
专利权人:
FARMACÉUTICOS ROVI S A LAB
发明人:
GUTIERRO ADURIZ IBON,GUTIERRO ADURIZ IBON,FRANCO RODRÍGUEZ GUILLERMO,FRANCO RODRÍGUEZ GUILLERMO
申请号:
IN10673/DELNP/2014
公开号:
IN2014DN10673A
申请日:
2014.12.15
申请国别(地区):
IN
年份:
2015
代理人:
摘要:
<;p>;An injectable intramuscular depot composition suitable for forming an in situ solid implant in a body comprising a drug which is paliperidone and/or its pharmaceutical acceptable salts in any combination thereof a biocompatible copolymer based on lactic and glycolic acid having a monomer ratio of lactic to glycolic acid in the range from 50:50 and a DMSO solvent wherein the composition releases the drug with an immediate onset of action and continuously for at least 8 weeks and wherein the composition has a pharmacokinetic profile suitable for the formulation to be administered each 8 weeks or even longer periods.<;/p>;
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